Photosensitizers

Specific compounds can release reactive oxygen species upon irradiation by light. Applications of reactive oxygen species have emerged as the broad area ranging from cancer therapy to reduction of dangerous waste. We have extensively studied TiO2 and phthalocyanine as photosensitizers especially due to their favourable photophysical characteristics and the ability to tune properties of phthalocyanine by proper substitution.

Controlled release of singlet oxygen for self-cleaning processes. (Products)

Inhibition of bacterial and algae growth. (Phthalocyanine Product List)

Respiratory protective materials. (Phthalocyanine Product List)

Decomposition of harmful substances (hormones, therapeutics) from waste water. (Phthalocyanine Product List)

Products

Phthalocyanine derivatives

functionalized phthalocyanines (see Product List)

product list

Diketopyrrolopyrrole derivatives

functionalized diketopyrrolopyrroles (see Product List)

product list

References

1. Rakušan J., Karásková M., Holada K., Janoušková O. (COC): CZ 303355, 2012.
  - Způsob inaktivace patogenních prionů, fotosenzitizátor pro inaktivaci patogenních prionů a použití fotosenzitizátoru pro inaktivaci patogenních prionů
  - Method for inactivation of pathogenic prions, photosensitizer for the inactivation of pathogenic prions, and use of photosensitizer for the inactivation of pathogenic prions
2. Jančula D., Blahová , Karásková M., Maršálek B.: Water Sci. Technol. 2010, 62(2), 273-278.
  Degradation of natural toxins by phthalocyanines – example of cyanobacterial toxin, mycrocystin.
3. Černý J., Karásková M., Rakušan J., Nešpůrek S.: Photochem. Photobiol. A 2010, 210, 82–88.
  Reactive oxygen species produced by irradiation of some phthalocyanine derivatives.
4. Jančula D., Maršálek B., Novotná Z., Černý J., Karásková M., Rakušan J.: Chemosphere 2009, 77, 1520.
  In search of the main properties of phthalocyanines participating in toxicity against cyanobacteria
5. Palewska K., Sujka M., Urasinska-Wojcik B., Sworakowski J., Lipinski J., Nešpůrek S., Černý J., Rakušan J., Karásková M.: Photochem. Photobiol., A 2008, 197, 1.
  Light-induced effects in sulfonated aluminum phthalocyanines potential photosensitizers in the photodynamic therapy
6. Stukavec J., Horák L., Ducháč V., Jirásek T., Rakušan J., Karásková M., Poučková P.: Neoplasma 2008, 55, 127.
  Soluble phthalocyanines: Photoconductivity-comparison of photodynamic therapy with phthalocyanine and photofrin in human colorectal carcinoma
7. Jančula D., Drábková M., Černý J., Karásková M., Kořínková R., Rakušan J., Maršálek B.: Enviroment. Toxicol. 2008, 23, 218.
  Algicidal activity of phthalocyanines - screening of 31 compounds